Brief asymmetric tonic posturing with diffuse low-voltage fast activity in seizures arising from the mesial parietal region

Abstract

Aim: Seizures originating from the parietal lobe can demonstrate variable semiology. Our aim was to describe the electroclinical features of seizures originating from the mesial parietal lobe. Method: We identified four patients through the Comprehensive Epilepsy Program at our institution, who had strong evidence of a mesial parietal source for their epilepsy, including a mesial parietal structural lesion. Results: Patients had very frequent brief seizures despite anticonvulsants, each lasting 10-30. s, with rapid return of awareness post-event. Clinically attacks were bland, or showed asymmetric tonic posturing, often with partially preserved awareness. Ictal EEG showed diffuse low voltage..